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PHA 568487
CAS No. 527680-56-4
PHA 568487 ( —— )
Catalog No. M24500 CAS No. 527680-56-4
The quinuclidine PHA 568487 is an agonist of the alpha 7 nicotinic acetylcholine receptor that was designed to mitigate the bioactivation associated with the core scaffold and subsequently remove associated liabilities with in vivo tolerability.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 31 | In Stock |
|
| 5MG | 50 | In Stock |
|
| 10MG | 80 | In Stock |
|
| 25MG | 152 | In Stock |
|
| 50MG | 282 | In Stock |
|
| 100MG | 507 | In Stock |
|
| 500MG | 1062 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePHA 568487
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NoteResearch use only, not for human use.
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Brief DescriptionThe quinuclidine PHA 568487 is an agonist of the alpha 7 nicotinic acetylcholine receptor that was designed to mitigate the bioactivation associated with the core scaffold and subsequently remove associated liabilities with in vivo tolerability.
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DescriptionThe quinuclidine PHA 568487 is an agonist of the alpha 7 nicotinic acetylcholine receptor that was designed to mitigate the bioactivation associated with the core scaffold and subsequently remove associated liabilities with in vivo tolerability.
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetAChR
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Recptorα7 nicotinic acetylcholine receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number527680-56-4
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Formula Weight288.3
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Molecular FormulaC16H20N2O3
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Purity>98% (HPLC)
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SolubilityH2O:<40.44mg/ml (100mM); DMSO:<40.44mg/ml (100mM)
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SMILESO=C(c(cc1)cc2c1OCCO2)N[C@@H]1C(CC2)CCN2C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Shilliday F, et al. Multiple species metabolism of PHA-568487, a selective alpha 7 nicotinic acetylcholine receptor agonist. Drug Metab Lett. 2010 Aug;4(3):162-72.
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